HEK293 - ATXN3 (KO) Cell Line
Datasheet
Key Features
Cat. No.:
NTV-0925-YJ346
Species
Human
Related Disease
Spinocerebellar ataxia type 3 (Machado-Joseph disease)
Summary
| Description | An HEK293 cell line in which the ATXN3 gene, encoding Ataxin-3, has been deleted. This model is critical for studying the protein's function as a deubiquitinating enzyme and for investigating the pathogenesis of spinocerebellar ataxia type 3. |
| Species | Human |
| Size | 1×10⁶ cells |
| Growth Conditions | 37°C with 5% CO₂ |
| Related Disease | Spinocerebellar ataxia type 3 (Machado-Joseph disease) |
| Synonyms | HEK293 Ataxin 3 Knockout cells; ATXN3-deficient HEK293 cells; HEK293 ATXN3-null cell line; HEK293 with Ataxin 3 gene knockout; ATXN3 KO 293 cells |
| Parental cells | HEK293 |
| Format | Frozen |
| Shipping | Dry Ice |
| Storage | Store in liquid nitrogen. |
Specifications
| Mycoplasma Testing | Negative |
| Cryopreservation Medium | 95% Complete Culture Medium with 5% DMSO |
| Research Use Only | For Research Use Only. Not For Clinical Use. |
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