HEK293 - GM2A (KO) Cell Line
Datasheet
Key Features
Cat. No.:
NTV-0925-YJ325
Species
Human
Related Disease
GM2-gangliosidosis, AB variant (Tay-Sachs/Sandhoff-like disease)
Summary
| Description | This HEK293 cell line has the GM2A gene, encoding the GM2 ganglioside activator protein, knocked out. It is a fundamental tool for studying the lysosomal degradation of gangliosides and for modeling GM2 gangliosidoses like Tay-Sachs disease. |
| Species | Human |
| Size | 1×10⁶ cells |
| Growth Conditions | 37°C with 5% CO₂ |
| Related Disease | GM2-gangliosidosis, AB variant (Tay-Sachs/Sandhoff-like disease) |
| Synonyms | HEK293 GM2A Knockout cells; GM2A-deficient HEK293 cells; HEK293 GM2A-null cell line; HEK293 with GM2A gene knockout; GM2A KO 293 cells |
| Parental cells | HEK293 |
| Format | Frozen |
| Shipping | Dry Ice |
| Storage | Store in liquid nitrogen. |
Specifications
| Mycoplasma Testing | Negative |
| Cryopreservation Medium | 95% Complete Culture Medium with 5% DMSO |
| Research Use Only | For Research Use Only. Not For Clinical Use. |
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