Neuroscience research typically focuses on the study of proteins and biomarkers associated with various aspects of brain function, including neuronal development, neural stem cells, neurodegenerative diseases, neuroinflammation, etc. ELISA plays a key role in detecting and quantifying these targets, providing valuable insights into the underlying mechanisms and potential therapeutic strategies for neurological disorders.
Here, Creative Biolabs will focus on these common ELISA targets involved in the field of neuroscience to help you advance your scientific research.
The Blood Brain Barrier (BBB) consists of a network of blood vessels that form a structural and chemical barrier between the brain and the body circulation. The limited permeability of the blood-brain barrier protects the brain from molecules that are harmless to peripheral organs, but toxic to brain neurons.
Listed below are some blood-brain barrier-related research targets that may be useful for your research.
Targets | |
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Blood brain barrier-related research targets |
A Disintegrin And Metalloprotease 8 (ADAM8) Total Advanced Glycosylation End Product Specific Receptor (AGER) Activated Leukocyte Cell Adhesion Molecule (ALCAM) Cytokeratin 18 (CK-18/KRT18) Claudin 5 (CLDN5) E-Cadherin (E-Cad) Galectin 1 (GAL1) Glial Fibrillary Acidic Protein (GFAP) Hepatocyte Growth Factor (HGF) Microtubule Associated Protein Tau/Tau Protein (MAPτ) Myelin Basic Protein (MBP) Matrix Metalloproteinase 1 (MMP-1) Matrix Metalloproteinase 2 (MMP-2) Matrix Metalloproteinase 3 (MMP-3) Nitric Oxide Synthase 1, Neuronal (NOS1/nNOS) Nephrin (NPHN) Platelet/Endothelial Cell Adhesion Molecule 1 (PECAM1/CD31) Syndecan 1 (SDC1) Thrombospondin-1 (TSP-1) Vascular Cell Adhesion Molecule 1 (VCAM-1/CD106) Vascular Endothelial Cadherin (VE-Cadherin) |
Neural stem cells originate from the ectoderm, are the most primitive and undifferentiated cells of the nervous system, and are thought to differentiate into a large number of specialized neural cells. Neural stem cells have characteristics such as multidirectional differentiation, self-renewal, tissue fusion, and immunogenicity, and are a key area of research in neuroscience.
Targets | |
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Neural stem cell-related targets |
Acetylcholinesterase (AChE) Activin A (ACV-A) Acidic Fibroblast Growth Factor 1 (AFGF/FGF1) Apolipoprotein E (ApoE) Amyloid Beta 1-40 (Aβ1-40) Amyloid Beta 1-42 (Aβ1-42) Brain Derived Neurotrophic Factor (BDNF) Basic Fibroblast Growth Factor (bFGF/FGF2) Chemokine C-X-C-Motif Receptor 4 (CXCR4) Fibroblast Growth Factor 21 (FGF21) Fibroblast Growth Factor 23 (FGF23) Galectin 3 (GAL3) Glial Fibrillary Acidic Protein (GFAP) Insulin-Like Growth Factor 1 (IGF-1) Interleukin 1 Beta (IL-1β) Interleukin 6 (IL-6) Inhibin B (INHB) Microtubule Associated Protein Tau/Tau Protein (MAPτ) Nuclear Factor, Erythroid Derived 2, Like 2 (NFE2L2) Placental Growth Factor (PGF) S100 Calcium Binding Protein B (S100B) Synuclein Alpha (SNCα) Synaptophysin (SYP) Transforming Growth Factor Beta 1 (TGF-β1) Vascular Endothelial Cell Growth Factor A (VEGF-A) |
Common neurodegenerative diseases include Alzheimer's disease, Parkinson's disease, myasthenia gravis, and psychiatric disorders including depression and anxiety related disorders. Understanding the pathogenesis of neurodegenerative diseases is critical to their prevention and treatment, and we offer a range of ELISA indicators for the study of biological processes that accompany neurodegenerative diseases.
Targets | |
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Neurodegenerative diseases-related targets |
Acidic Fibroblast Growth Factor 1 (AFGF/FGF1) Apolipoprotein E (ApoE) Basic Fibroblast Growth Factor (bFGF/FGF2) Glial Cell Line Derived Neurotrophic Factor (GDNF) Heat Shock Protein 27 (HSP-27/HSPB1) Insulin-like Growth Factor 1 (IGF-1) Insulin Like Growth Factor 1 Receptor (IGF1R) Interleukin 6 (IL-6) Interleukin 6 Receptor (IL-6R) Interleukin 34 (IL-34) Klotho (KL) Microtubule Associated Protein Tau/Tau Protein (MAPτ) Neurofilament, Light Polypeptide (NEFL) Neuregulin 1 (NRG-1) Neurotrophin 3 (NT-3) Sirtuin 1 (SIRT1) Synuclein Alpha (SNCα) Tissue-type Plasminogen Activator (tPA) Ubiquitin (Ub) Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1) |
At Creative Biolabs, we share with you some of the ELISA targets involved in the field of neuroscience. Interested researchers can contact us for more information.
For Research Use Only. Not For Clinical Use.