Ba/F3 - ERBB2 Cell Line
Datasheet
Key Features
Cat. No.:
NTV-0825-YJ112
Species
Mouse
Related Disease
Brain Tumor; Multiple Sclerosis
Summary
| Description | This Ba/F3 cell line is engineered to express a constitutively active human ERBB2 tyrosine kinase as a GFP-ETV6-ERBB2 fusion. This modification results in IL-3 independent cell survival and proliferation, making it a powerful tool for screening potential ERBB2 inhibitors and studying oncogenic signaling. |
| Species | Mouse |
| Size | 1x10⁶ cells (1.0 ml) |
| Related Disease | Brain Tumor; Multiple Sclerosis |
| Format | Frozen |
| Shipping | Dry Ice |
| Storage | Store immediately in liquid nitrogen upon receipt. |
Specifications
| Warnings | For your protection, you must wear protective gloves, clothing, and a face mask when handling frozen vials. Bear in mind that some liquid seepage into the vial can occur during storage. Upon thawing, the liquid nitrogen turns into a gas. Due to the nature of nitrogen, this can cause pressure to build up inside the vial, potentially leading to the vial bursting or the cap ejecting. This creates a risk of flying debris. |
| Cryopreservation Medium | 90% complete growth medium plus 10% DMSO. |
| Research Use Only | For Research Use Only. Not For Clinical Use. |
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