Can I order custom models?

Yes, Creative Biolabs offers custom cell model services. We can work with you to develop models from specific genetic backgrounds or create unique co-culture systems. Contact our scientific team to discuss your needs.

What is the typical purity of the cell populations?

Our differentiation protocols are highly optimized to achieve >90% purity for the specified cell type. Lot-specific information is available on the Certificate of Analysis.

What is the expected viability upon thawing?

With adherence to our provided protocol, you can expect >90% viability.

How many cells are provided per vial?

Each vial typically contains ≥ 1 million viable cells, sufficient for seeding multiple wells depending on your experimental design.

Are these cells capable of proliferation?

Most of our models are terminally differentiated, post-mitotic cells (e.g., neurons). Progenitor cell models are available upon request for specific applications.

Online Inquiry

Cerebral Palsy Cell Model Products

Introduction Types Advantages Applications FAQs Related Product Sections Product List

Introduction

The study of Cerebral Palsy (CP) poses a significant challenge for researchers, owing to its varied origins and intricate pathophysiology. Making progress in elucidating its mechanisms and creating new treatments is contingent upon having experimental models that are both biologically accurate and reliable.

Creative Biolabs meets this need by providing scientists with an extensive portfolio of high-grade, iPSC-derived cerebral palsy cell models. Our products remove the bottleneck of in-house model creation, enabling your team to concentrate on its primary research goals. Grounded in meticulous scientific validation, our cell models offer the dependable, consistent in vitro systems necessary to advance your work. Connect with our specialists to discuss your Cerebral Palsy research needs and to receive a personalized quote for your project.

For the fastest way to find a product, browse our complete Product List.

Types

We offer a range of specific neural cell types, differentiated from CP patient-derived iPSCs, to target your precise research interest.

Types	Description
iPSC-Derived Neural Models	The cornerstone of our offerings. We provide patient-specific, gene-edited, and healthy control lines differentiated into pure populations of cortical neurons, motor neurons, astrocytes, oligodendrocytes, and microglia.
Co-Culture Systems	Advanced 2D and 3D models combining multiple cell types (e.g., neuron-astrocyte, neuron-oligodendrocyte) to study complex cellular interactions relevant to CP pathology.
Primary Cell Models	Sourced ethically and cryopreserved with high viability for specific comparative studies.

Advantages

Adopting Creative Biolabs' iPSC-derived platforms provides distinct, transformative advantages over conventional research methods, empowering you to ask and answer questions that were previously out of reach.

Unlock Unprecedented Clinical Translation

Our human-specific models bypass the limitations of animal studies. By using cells that activate human pathways, your data gains higher predictive validity for clinical trials, significantly de-risking your therapeutic development pipeline and increasing the chance of success.

Dissect Complex Disease Mechanisms with Cellular Precision

CP involves complex cell interactions. Our purified monocultures and defined co-cultures provide the precision to isolate variables and pinpoint the specific roles of neurons, astrocytes, and microglia. This control is essential for dissecting disease mechanisms and finding new targets.

Capture Patient-Specific Heterogeneity

Model Cerebral Palsy as the spectrum it truly is. Our models, derived from diverse patient donors with specific genetic backgrounds, allow you to investigate the basis of patient variability. This approach is fundamental for developing more effective, personalized therapies.

Enable High-Throughput Discovery and Screening

Overcome the limits of primary tissue scarcity. The unlimited supply of our iPSC-derived cells is fully compatible with automated High-Throughput Screening (HTS). This scalability allows you to screen thousands of compounds rapidly, accelerating the discovery of novel drug candidates.

Enhance Predictive Toxicology and Safety Assessment

Identify neurotoxic liabilities much earlier in development. Our human neural models allow you to perform predictive safety screening before committing to costly trials. This "fail early" strategy saves critical time and resources by focusing your efforts only on the most promising compounds.

Applications

You can seamlessly integrate our versatile human iPSC-derived neural models at every stage of the drug discovery and development pipeline. Creative Biolabs provides a biologically relevant and reproducible platform that empowers you to tackle critical scientific questions with enhanced speed and certainty. Our models are expertly optimized for a broad spectrum of advanced applications:

Applications	Description
Drug Discovery & High-Throughput Screening (HTS)	Screen compound libraries to identify novel therapeutic candidates that can mitigate neuronal damage or promote repair.
Disease Mechanism Studies	Elucidate the complex cellular and molecular pathways underlying CP, including excitotoxicity, oxidative stress, and neuroinflammation.
Myelination & White Matter Injury Research	Use our iPSC-derived oligodendrocyte models to study developmental myelination processes and screen for remyelination-promoting agents.
Neuroinflammation & Gliosis Research	Investigate the role of astrocytes and microglia in the inflammatory cascades associated with perinatal brain injury.
Personalized Medicine	Utilize patient-specific iPSC models to understand how different genetic backgrounds influence disease presentation and therapeutic response.
Toxicology & Safety Assays	Assess the neurotoxic potential of new compounds on developing human neural cells.

A picture that presents FNC in the three groups. (Qin, et al., 2018) (OA Literature)

Fig.1 FNC in the three groups.¹

FAQs

Can I order custom models?
Yes, Creative Biolabs offers custom cell model services. We can work with you to develop models from specific genetic backgrounds or create unique co-culture systems. Contact our scientific team to discuss your needs.
What is the typical purity of the cell populations?
Our differentiation protocols are highly optimized to achieve >90% purity for the specified cell type. Lot-specific information is available on the Certificate of Analysis.
What is the expected viability upon thawing?
With adherence to our provided protocol, you can expect >90% viability.
How many cells are provided per vial?
Each vial typically contains ≥ 1 million viable cells, sufficient for seeding multiple wells depending on your experimental design.
Are these cells capable of proliferation?
Most of our models are terminally differentiated, post-mitotic cells (e.g., neurons). Progenitor cell models are available upon request for specific applications.

Creative Biolabs offers an extensive selection of Cerebral Palsy cell models and associated services for researchers in both academia and industry. Our mission is to provide high-grade, biologically accurate, and consistent tools to hasten the development of new treatments for neurodevelopmental disorders. Contact our specialists for a consultation on your project requirements and for guidance in selecting the optimal model for your research.