Can you create a custom neural model if I don't see the specific disease or mutation I need?

Absolutely. We offer comprehensive custom cell model development services. Our team can work with you to design and create a model with the specific genetic modification or cellular background your project requires. Please contact us to discuss your needs.

How long can I maintain these cells in culture?

This varies by cell type. Neurons are terminally differentiated, while glial progenitor cells can be expanded. The CoA and protocol provide specific guidance.

For your stroke models, do you induce ischemic conditions?

Our stroke models are optimized to respond to classic in vitro ischemic insults like oxygen-glucose deprivation (OGD), providing a robust system to test neuroprotective agents.

Do you provide technical support if I have trouble?

Yes, our team of dedicated scientists is available to help you troubleshoot any issues with cell culture or experimental setup.

Can I get a discount for a bulk order?

Yes, we offer competitive pricing and discounts for bulk or standing orders. Please contact our sales team for a custom quote.

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Other Notable Disease related Research Tools

Introduction Types Advantages Applications FAQs Related Product Sections Product List

Introduction

Neuroscience has made incredible strides, yet many debilitating neurological conditions remain outside the mainstream focus of Alzheimer's and Parkinson's research. For scientists dedicated to studying epilepsy, stroke, brain tumors, and other complex disorders, finding reliable, clinically relevant in vitro tools is a constant challenge.

Creative Biolabs understands that a breakthrough in one of these areas is just as critical as any other. That's why we've developed a unique portfolio of high-quality neural cell models for a range of notable neurological diseases. These are not just cells in a vial; they are meticulously characterized, ready-to-use systems designed to accelerate your research and bring you closer to actionable insights.

Let our team help you find the perfect model for your project. Request a Quote >

A detailed summary of our offerings can be found in the complete Product List.

Available Cell Model Types

Our portfolio provides specialized tools for investigating the cellular and molecular underpinnings of these complex conditions.

Advantages

Choosing the right cellular model is the foundation of successful preclinical research. Our commitment to scientific excellence ensures that our neural cell products provide the accuracy, reproducibility, and clinical relevance your project demands.

Skip the Development, Start the Discovery

Save months of in-house development and validation. Our models allow you to focus immediately on your core research questions.

Achieve Clinical Relevance

Work with models designed to mimic human disease, increasing the translational potential of your findings for drug screening and mechanistic studies.

Ensure Reproducibility

Our stringent quality control processes mean you get highly consistent, low-variation cell populations. Every cell batch undergoes rigorous validation, including immunocytochemistry for marker expression and functional assays (e.g., MEA, calcium imaging), leading to more reliable and publishable data.

Access Expert Support

You're not just buying a product. You gain access to our team of PhD-level neuroscientists who can provide technical support and help you get the most out of your experiments.

Customization is Standard

If our catalog models don't perfectly fit your needs, we will build one that does. Our custom cell model development service is here to support your unique research goals.

Applications

Our rare and metabolic disease neural models are engineered to serve a wide array of research and preclinical applications, providing critical human-specific data to accelerate therapeutic programs.

Applications	Description
Therapeutic Discovery & Drug Screening	High-Throughput Screening (HTS): Utilize our robust, plate-based models to screen large libraries of small molecules, biologics, or antisense oligonucleotides (ASOs) for desired phenotypic effects. Efficacy Testing & Lead Optimization: Characterize lead compounds with detailed dose-response analyses to confirm on-target effects and therapeutic potential. Target Identification & Validation: Use our models in conjunction with genetic tools like CRISPR/Cas9 to identify and validate novel molecular targets responsible for disease phenotypes.
Mechanistic & Basic Research	Disease Pathogenesis Studies: Dissect the fundamental cellular and molecular cascades underlying neurological disorders, from network hyperexcitability in epilepsy to autoimmune-mediated damage in PNS. Investigating Genetic Drivers: Model-specific patient mutations to understand how they lead to cellular dysfunction, providing a direct link between genotype and phenotype. Analysis of Cell-Cell Interactions: Our complex co-culture systems allow for the detailed study of the interplay between neurons and glial cells (astrocytes, microglia, oligodendrocytes) during health and disease.
Preclinical Safety & Toxicity Assessment	Neurotoxicity Screening: Evaluate the potential neurotoxic effects of drug candidates early in the development pipeline to flag problematic compounds and reduce late-stage failures. Off-Target Effect Profiling: Assess the impact of compounds developed for non-CNS indications on the health and function of human neural networks. Personalized Medicine Approaches: For certain conditions, models derived from patient-specific iPSCs can help predict individual responses to a given therapy, paving the way for stratified clinical trials.

A picture that presents the molecular targets for the treatment of epilepsy. (Boleti, et al., 2024) (OA Literature)

Fig.1 Epileptogenesis is activated by neuroinflammation and the molecular targets for the treatment of epilepsy.¹

FAQs

Can you create a custom neural model if I don't see the specific disease or mutation I need?
Absolutely. We offer comprehensive custom cell model development services. Our team can work with you to design and create a model with the specific genetic modification or cellular background your project requires. Please contact us to discuss your needs.
How long can I maintain these cells in culture?
This varies by cell type. Neurons are terminally differentiated, while glial progenitor cells can be expanded. The CoA and protocol provide specific guidance.
For your stroke models, do you induce ischemic conditions?
Our stroke models are optimized to respond to classic in vitro ischemic insults like oxygen-glucose deprivation (OGD), providing a robust system to test neuroprotective agents.
Do you provide technical support if I have trouble?
Yes, our team of dedicated scientists is available to help you troubleshoot any issues with cell culture or experimental setup.
Can I get a discount for a bulk order?
Yes, we offer competitive pricing and discounts for bulk or standing orders. Please contact our sales team for a custom quote.

Don't let the complexity of neurological disease slow your progress. Leverage the power of Creative Biolabs' advanced neural cell products to gain deeper insights and drive your next breakthrough discovery. Contact our scientific team today to discuss your project, request a quote, or learn more about how our validated models can become a seamless extension of your laboratory.