BV2 - NLRP3 (KO) Cell Line
Datasheet
Key Features
Cat. No.:
NTV-0925-YJ139
Species
Mouse
Related Disease
Autoinflammatory syndromes with neurological symptoms
Summary
| Description | This BV2 cell line has the NLRP3 gene inactivated using advanced CRISPR/Cas9 technology. It provides a clean genetic background to investigate the specific roles of the NLRP3 inflammasome in neuroinflammation and innate immunity without off-target effects. |
| Species | Mouse |
| Size | 1×10⁶ cells |
| Growth Conditions | 37°C with 5% CO₂ |
| Related Disease | Autoinflammatory syndromes with neurological symptoms |
| Synonyms | BV2 NLRP3 Knockout cells; NLRP3-deficient BV2 cells; BV2 NLRP3-null cell line; BV2 cells with NLRP3 gene knockout; NLRP3 KO BV2 microglial cells |
| Parental cells | BV2 |
| Format | Frozen |
| Shipping | Dry Ice |
| Storage | Store in liquid nitrogen. |
Specifications
| Mycoplasma Testing | Negative |
| Cryopreservation Medium | 70% Complete Culture Medium with 20% FBS and 10% DMSO |
| Research Use Only | For Research Use Only. Not For Clinical Use. |
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