BV2 - TREM2 (KO) Cell Line
Datasheet
Key Features
Cat. No.:
NTV-0925-YJ140
Species
Mouse
Related Disease
Alzheimer's disease, Nasu-Hakola disease
Summary
| Description | A BV2 cell line in which the Trem2 gene has been precisely deleted using an optimized CRISPR/Cas9 approach. This model is invaluable for studying the function of Trem2 in microglial phagocytosis, lipid metabolism, and its contribution to neurodegenerative diseases. |
| Species | Mouse |
| Size | 1×10⁶ cells |
| Growth Conditions | 37°C with 5% CO₂ |
| Related Disease | Alzheimer's disease, Nasu-Hakola disease |
| Synonyms | BV2 TREM2 Knockout cells; TREM2-deficient BV2 cells; BV2 TREM2-null cell line; BV2 cells with TREM2 gene knockout; TREM2 KO BV2 microglial cells |
| Parental cells | BV2 |
| Format | Frozen |
| Shipping | Dry Ice |
| Storage | Store in liquid nitrogen. |
Specifications
| Mycoplasma Testing | Negative |
| Cryopreservation Medium | 70% Complete Culture Medium with 20% FBS and 10% DMSO |
| Research Use Only | For Research Use Only. Not For Clinical Use. |
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