HEK293 - GRN (KO) Cell Line
Datasheet
Key Features
Cat. No.:
NTV-0925-YJ279
Species
Human
Related Disease
Frontotemporal dementia
Summary
| Description | This HEK293 cell line features a knockout of the GRN gene, which encodes progranulin. It is a critical in vitro model for studying the pathogenesis of frontotemporal dementia and for investigating the role of progranulin in lysosomal function and neuroinflammation. |
| Species | Human |
| Size | 1×10⁶ cells |
| Growth Conditions | 37°C with 5% CO₂ |
| Related Disease | Frontotemporal dementia |
| Synonyms | HEK293 Progranulin Knockout cells; GRN-deficient HEK293 cells; HEK293 GRN-null cell line; HEK293 with Progranulin gene knockout; GRN KO 293 cells |
| Parental cells | HEK293 |
| Format | Frozen |
| Shipping | Dry Ice |
| Storage | Store in liquid nitrogen. |
Specifications
| Mycoplasma Testing | Negative |
| Cryopreservation Medium | 95% Complete Culture Medium with 5% DMSO |
| Research Use Only | For Research Use Only. Not For Clinical Use. |
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