HEK293 - NDUFS2 Knockout Cell Line

Datasheet Datasheet

Key Features

Cat. No.:

NTV-0825-YJ303

Species

Human

Related Disease

Leigh Syndrome

Size:

Summary
Description This HEK293 cell line has a permanent, CRISPR-mediated knockout of NDUFS2, a core subunit of mitochondrial Complex I. The resulting cells exhibit impaired Complex I respiration and slower growth, making them a valuable model for studying mitochondrial dysfunction and evaluating mitochondrial therapeutics.
Species Human
Size 1x10⁶ cells (1.0 ml)
Related Disease Leigh Syndrome
Format Frozen
Shipping Dry Ice
Storage Store immediately in liquid nitrogen upon receipt.
Specifications
Warnings For your protection, you must wear protective gloves, clothing, and a face mask when handling frozen vials. Bear in mind that some liquid seepage into the vial can occur during storage. Upon thawing, the liquid nitrogen turns into a gas. Due to the nature of nitrogen, this can cause pressure to build up inside the vial, potentially leading to the vial bursting or the cap ejecting. This creates a risk of flying debris.
Cryopreservation Medium 90% complete growth medium plus 10% DMSO.
Research Use Only For Research Use Only. Not For Clinical Use.
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For Research Use Only. Not For Clinical Use.

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