HEK293 - OPTN (KO) Cell Line
Datasheet
Key Features
Cat. No.:
NTV-0925-YJ217
Species
Human
Related Disease
Amyotrophic lateral sclerosis (ALS), Normal-tension glaucoma
Summary
| Description | This HEK293 cell line has a targeted deletion of the OPTN gene, created with an optimized CRISPR/Cas9 system. It is a critical model for investigating the roles of optineurin in autophagy, NF-κB signaling, and the pathogenesis of glaucoma and ALS. |
| Species | Human |
| Size | 1×10⁶ cells |
| Growth Conditions | 37°C with 5% CO₂ |
| Related Disease | Amyotrophic lateral sclerosis (ALS), Normal-tension glaucoma |
| Synonyms | HEK293 Optineurin Knockout cells; OPTN-deficient HEK293 cells; HEK293 OPTN-null cell line; HEK293 with OPTN gene knockout; OPTN KO 293 cells |
| Parental cells | HEK293 |
| Format | Frozen |
| Shipping | Dry Ice |
| Storage | Store in liquid nitrogen. |
Specifications
| Mycoplasma Testing | Negative |
| Cryopreservation Medium | 95% Complete Culture Medium with 5% DMSO |
| Research Use Only | For Research Use Only. Not For Clinical Use. |
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