HEK293T - NPC1 (KO) Cell Line
Datasheet
Key Features
Cat. No.:
NTV-0925-YJ145
Species
Human
Related Disease
Niemann-Pick disease, type C
Summary
| Description | A 293T cell line with the NPC1 gene fully knocked out by an optimized CRISPR/Cas9 process. This line is a critical resource for studying the cellular mechanisms of cholesterol trafficking and for modeling the lysosomal storage defects seen in Niemann-Pick disease, type C. |
| Species | Human |
| Size | 1×10⁶ cells |
| Growth Conditions | 37°C with 5% CO₂ |
| Related Disease | Niemann-Pick disease, type C |
| Synonyms | 293T NPC1 Knockout cells; NPC1-deficient 293T cells; 293T NPC1-null cell line; 293T cells with NPC1 gene knockout; NPC1 KO HEK293T cells |
| Parental cells | HEK293T |
| Format | Frozen |
| Shipping | Dry Ice |
| Storage | Store in liquid nitrogen. |
Specifications
| Mycoplasma Testing | Negative |
| Cryopreservation Medium | 95% Complete Culture Medium with 5% DMSO |
| Research Use Only | For Research Use Only. Not For Clinical Use. |
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