HEK293T - OPTN (KO) Cell Line
Datasheet
Key Features
Cat. No.:
NTV-0925-YJ143
Species
Human
Related Disease
Amyotrophic lateral sclerosis (ALS), Normal-tension glaucoma
Summary
| Description | An OPTN knockout cell line generated in the 293T background using a refined CRISPR/Cas9 methodology. This cellular model is essential for dissecting the roles of optineurin in cellular processes like autophagy and vesicle trafficking, particularly in the context of glaucoma and ALS research. |
| Species | Human |
| Size | 1×10⁶ cells |
| Growth Conditions | 37°C with 5% CO₂ |
| Related Disease | Amyotrophic lateral sclerosis (ALS), Normal-tension glaucoma |
| Synonyms | 293T OPTN Knockout cells; Optineurin-deficient 293T cells; 293T OPTN-null cell line; 293T cells with OPTN gene knockout; OPTN KO HEK293T cells |
| Parental cells | HEK293T |
| Format | Frozen |
| Shipping | Dry Ice |
| Storage | Store in liquid nitrogen. |
Specifications
| Mycoplasma Testing | Negative |
| Cryopreservation Medium | 95% Complete Culture Medium with 5% DMSO |
| Research Use Only | For Research Use Only. Not For Clinical Use. |
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