THP-1 - TREM2 Knockout Cell Line
Datasheet
Key Features
Cat. No.:
NTV-0825-YJ301
Species
Human
Related Disease
Alzheimer's Disease
Summary
| Description | This THP-1 human monocytic cell line has a permanent knockout of the TREM2 gene, generated by CRISPR. It is a valuable model for investigating the role of TREM2, a key receptor in microglia and macrophages, in neuro-inflammation, phagocytosis, and Alzheimer's disease pathology. |
| Species | Human |
| Size | 1x10⁶ cells (1.0 ml) |
| Related Disease | Alzheimer's Disease |
| Format | Frozen |
| Shipping | Dry Ice |
| Storage | Store immediately in liquid nitrogen upon receipt. |
Specifications
| Warnings | For your protection, you must wear protective gloves, clothing, and a face mask when handling frozen vials. Bear in mind that some liquid seepage into the vial can occur during storage. Upon thawing, the liquid nitrogen turns into a gas. Due to the nature of nitrogen, this can cause pressure to build up inside the vial, potentially leading to the vial bursting or the cap ejecting. This creates a risk of flying debris. |
| Cryopreservation Medium | 90% complete growth medium plus 10% DMSO. |
| Research Use Only | For Research Use Only. Not For Clinical Use. |
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